The Laboratory of Measurements and Instrumentation of the University of Salento has been active for years in the field of applied research, through the design, implementation and characterization of ad-hoc innovative monitoring systems, mainly (but not only) based on microwave techniques. The applications of these systems range over different fields, from t leaks in underground water and sewage pipes to monitoring production processes and monitoring vital parameters in the biomedical field. The research work is constantly focused on development on innovative systems and improving the real-time response, reliability and high measurement accuracy.